Dr. Kandil and his team are passionate advocates for thyroid nodule ablations.
Ablation therapy can treat thyroid nodules without any surgery
Dr. Kandil has trained extensively in the use of radio-frequency and microwave ablations for thyroid nodules outside the USA where this approach was used for years before FDA clearance here at home
He is the first specialist to perform 1,000+ radio-frequency ablations for thyroid nodules in the USA
Physicians from all over the world regularly travel to New Orleans to learn from Dr. Kandil regarding these procedures
Our research team has been involved in extensive work regarding radio-frequency and microwave ablations for thyroid nodules:
Russell JO, Huber T, Noel J, Papaleontiou M, Baldwin CK, Banuchi VM, Dhillon V, Dream S, Hodak SP, Kandil E, Kuo JH, Patel KN, Sinclair CF, Tufano RP. Letter to the Editor: New Current Procedural Terminology Codes for Radiofrequency Ablation of Thyroid Nodules Will Negatively Affect American Patients According to the Executive Council of the North American Society for Interventional Thyroidology. Thyroid. 2025 Feb;35(2):225-226. doi: 10.1089/thy.2024.0722. Epub 2025 Jan 24. PMID: 39853233.
Toraih E, Hussein M, Elshazli R, Abdelmaksoud A, AbdAlnaeem MA, Bashumeel YY, Bobba T, Bishop J, Paladugu S, Leei GS, Kandil E. Therapeutic outcomes and safety of radiofrequency ablation for primary papillary thyroid carcinoma: A game-changing meta-analysis. Radiother Oncol. 2025 Apr;205:110706. doi: 10.1016/j.radonc.2025.110706. Epub 2025 Jan 23. PMID: 39862924.
Kandil E, Hussein MH, Sugumar K, Patel M, Russell M, Randolph G, Toraih EA. Cytological Alterations of Benign Thyroid Nodules Following Radiofrequency Ablation. Laryngoscope. 2025 Mar 21. doi: 10.1002/lary.32130. Epub ahead of print. PMID: 40116363.
Luo X, Kandil E. Microwave ablation: a technical and clinical comparison to other thermal ablation modalities to treat benign and malignant thyroid nodules. Gland Surg. 2024 Oct 31;13(10):1805-1813. doi: 10.21037/gs-24-221. Epub 2024 Oct 26. PMID: 39544972; PMCID: PMC11558300.
LaForteza, A., Persons, E., Hussein, M., Luo, X., Issa, P., Jishu, J., Shama, M., Toraih, E., & Kandil, E. Treatment outcomes in patients with papillary thyroid cancer undergoing radiofrequency ablation of metastatic lymph nodes. Gland Surgery. 2024 Oct;13(10):1752-1758. doi:10.21037/gs-24-285
Russell JO, Desai DD, Noel JE, Hussein M, Toraih E, Seo S, Wolfe S, Omar M, Issa P, Orloff LA, Tufano RP, Kandil E. Radiofrequency ablation of benign thyroid nodules: A prospective, multi-institutional North American experience. Surgery. 2024 Jan;175(1):139-145. doi: 10.1016/j.surg.2023.07.046. Epub 2023 Nov 10. PMID: 37953141.
Hussein M, Toraih E, Issa PP, Omar M, Aboueisha M, Buti Y, Issa CP, Albuck AL, Cironi K, Attia AS, LaForteza AC, Shama M, Kandil E. From ablation to operation: Unraveling the surgical outcomes and complications of thyroidectomy after radiofrequency ablation. Surgery. 2024 Jan;175(1):146-152. doi: 10.1016/j.surg.2023.09.025. Epub 2023 Oct 20. PMID: 37867100.
Mueller LE, Issa PP, Hussein MH, Elshazli RM, Haidari M, Errami Y, Shama M, Fawzy MS, Kandil E, Toraih E. Clinical outcomes and tumor microenvironment response to radiofrequency ablation therapy: a systematic review and meta-analysis. Gland Surg. 2024 Jan 29;13(1):4-18. doi: 10.21037/gs-22-555. Epub 2023 Jul 24. PMID: 38323236; PMCID: PMC10839696.
Issa PP, Kandil E, Lee GS. Radiofrequency ablation as a treatment modality for primary hyperparathyroidism: a systematic literature review. Gland Surg. 2024 Jan 29;13(1):87-99. doi: 10.21037/gs-22-546. Epub 2023 Jun 14. PMID: 38323227; PMCID: PMC10839703.
Issa PP, Cironi K, Rezvani L, Kandil E. Radiofrequency ablation of thyroid nodules: a clinical review of treatment complications. Gland Surg. 2024 Jan 29;13(1):77-86. doi: 10.21037/gs-22-539. Epub 2023 Jun 20. PMID: 38323235; PMCID: PMC10839694.
Issa PP, Magazine BM, LaForteza A, Shama M, Kandil E. Bilateral nodule radiofrequency ablation in a single setting: First reported case series. Head Neck. 2023 Nov;45(11):2749-2753. doi: 10.1002/hed.27494. Epub 2023 Sep 5. PMID: 37667677.
Kandil E, Issa PP, Randolph GW. Can Thyroid Nodules be Managed with Radiofrequency Ablation? Adv Surg. 2023 Sep;57(1):87-101. doi: 10.1016/j.yasu.2023.05.004. Epub 2023 Jun 28. PMID: 37536864.
Kandil E, Haidari M, Issa PP, Omar M, Shama M. Radiofrequency ablation of an intrathyroidal parathyroid adenoma with intraoperative parathyroid hormone monitoring: a case report of a novel technique. Gland Surg. 2023 May 30;12(5):704-709. doi: 10.21037/gs-22-733. Epub 2023 Apr 14. PMID: 37284717; PMCID: PMC10240429.
Kandil E, Omar M, Aboueisha M, Attia AS, Ali KM, Abu Alhuda RF, Issa PP, Wolfe S, Omari S, Buti Y, Abozaid O, Toraih E, Shama MA, Lee G, Tufano RP, Russell JO. Efficacy and Safety of Radiofrequency Ablation of Thyroid Nodules: A Multi-institutional Prospective Cohort Study. Ann Surg. 2022 Oct 1;276(4):589-596. doi: 10.1097/SLA.0000000000005594. Epub 2022 Jul 15. PMID: 35837903.
Issa PP, Omar M, Issa CP, Buti Y, Hussein M, Aboueisha M, Abdelhady A, Shama M, Lee GS, Toraih E, Kandil E. Radiofrequency Ablation of Indeterminate Thyroid Nodules: The First North American Comparative Analysis. Int J Mol Sci. 2022 Sep 29;23(19):11493. doi: 10.3390/ijms231911493. PMID: 36232815; PMCID: PMC9569520.
Kandil E, Omar M, Attia AS, Shihabi A, Shaear M, Metz T, Issa PP, Russell JO, Tufano RP. Radiofrequency ablation as a novel modality in the USA for treating toxic thyroid nodules: case series and literature review. Gland Surg. 2022 Sep;11(9):1574-1583. doi: 10.21037/gs-22-35. PMID: 36221276; PMCID: PMC9547704.
Orloff LA, Noel JE, Stack BC Jr, Russell MD, Angelos P, Baek JH, Brumund KT, Chiang FY, Cunnane MB, Davies L, Frasoldati A, Feng AY, Hegedüs L, Iwata AJ, Kandil E, Kuo J, Lombardi C, Lupo M, Maia AL, McIver B, Na DG, Novizio R, Papini E, Patel KN, Rangel L, Russell JO, Shin J, Shindo M, Shonka DC Jr, Karcioglu AS, Sinclair C, Singer M, Spiezia S, Steck JH, Steward D, Tae K, Tolley N, Valcavi R, Tufano RP, Tuttle RM, Volpi E, Wu CW, Abdelhamid Ahmed AH, Randolph GW. Radiofrequency ablation and related ultrasound-guided ablation technologies for treatment of benign and malignant thyroid disease: An international multidisciplinary consensus statement of the American Head and Neck Society Endocrine Surgery Section with the Asia Pacific Society of Thyroid Surgery, Associazione Medici Endocrinologi, British Association of Endocrine and Thyroid Surgeons, European Thyroid Association, Italian Society of Endocrine Surgery Units, Korean Society of Thyroid Radiology, Latin American Thyroid Society, and Thyroid Nodules Therapies Association. Head Neck. 2022 Mar;44(3):633-660. doi: 10.1002/hed.26960. Epub 2021 Dec 23. PMID: 34939714.
Toraih EA, Fawzy MS, Hussein MH, El-Labban MM, Ruiz EML, Attia AA, Halat S, Moroz K, Errami Y, Zerfaoui M, Kandil E. MicroRNA-Based Risk Score for Predicting Tumor Progression Following Radioactive Iodine Ablation in Well-Differentiated Thyroid Cancer Patients: A Propensity-Score Matched Analysis. Cancers (Basel). 2021 Sep 16;13(18):4649. doi: 10.3390/cancers13184649. PMID: 34572876; PMCID: PMC8468667.
Fontenot, Tatyana E. BA; Bhatia, Parisha; Al-Qurayshi, Zaid MBChB, MPH; Kandil, Emad MBBCh, FACS. Percutaneous ethanol injection treatment vs radiofrequency ablation of locally recurrent papillary thyroid cancer: a systematic review and analysis. Journal of the American College of Surgeons 219(4):p e126-e127, October 2014. doi: 10.1016/j.jamcollsurg.2014.07.723
Dr. Kandil has presented extensively about thyroid ablation: